The Prevalence of Alzheimer's Disease Pathology After Traumatic Brain Injury in Veterans and Civilians: A Biomarker Study of Beta-Amyloid and Tau

Grant number: W81XWH-19-1-0746 | Funding period: 2019 - 2023

Completed

Abstract

PUBLIC ABSTRACT Background: Some old research studies have suggested that people with brain injuries maybe 400% more likely to lose their brain function due to a dementia called Alzheimer’s disease (AD). Modern studies have yet to be able to confirm a direct link. Two modern brain scans called Amyloid-PET and Tau-PET can now measure directly the plaques in the brain caused by AD. In addition another modern brain scan 7T-MRI can also measure other brain abnormalities like bleeding, loss of brain cells, and micro-strokes. Specific Aims: (1) Measure plaques in the brain caused by AD using these modern PET brain scans in Vietnam Veterans and car accident victims. (2) Measure other brain injuries..

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